USANA issued landmark patent for InCelligence Complex formula featured in their CellSentials supplement.
With its U.S. patent-pending cell-signaling InCelligence Complex, USANA has created a cutting-edge product to support your body’s natural ability to make its own protective antioxidants, which are even stronger than those in just about any supplement. CellSentials™ contains a triple-action system that protects, renews, and nourishes cells for optimal cellular function.*
So what does all this really mean? Let’s hear from the expert:
“Our bodies are made up of trillions of cells and many of them are constantly generating cellular energy to power processes in our bodies, like our heartbeat,” says Executive Vice President of Research and Development Dr. Kevin Spelman. “But this process can also generate free radicals that can damage the mitochondria within the cell. Fortunately, our cells have a natural process that helps clean any damaged mitochondria out of the cell to help renew efficient cellular function. Cellsentials help activate this process.”
Also launching with USANA’s InCelligence Technology is their newest product Proglucamune™, an immune-support supplement. Proglucamune is designed to help immune cells respond effectively and support the body’s ability to adapt to occasional stress.*
After years of hard work, research, and patience, USANA is proud to announce it has been issued a groundbreaking US patent for its InCelligence Complex formula. The patent, US Pat. No. 10,632,101, is unique to the health and wellness industry. It recognizes the InCelligence Complex formula contains antioxidant compounds that support endogenous systems associated with optimal lifespans. The patent was submitted by USANA R&D scientists, Drs. Mark Brown, Jeremy Tian, and John Cuomo.*
“USANA has always been considered a pioneer in the health and wellness industry, and this patent separates us even further from the competition,” says Dr. Rob Sinnott, USANA’s chief scientific officer. “The patent process is not an easy one, with just over 50 percent of all patents approved each year. For USANA to acquire one with such serious claims behind it shows how special our InCelligence Complex formulation truly is. I would like to thank Drs. Brown, Tian, and Cuomo for all their hard work on this project. What they have accomplished is a huge game changer for USANA.”
USANA’s InCelligence Complex is found in its flagship CellSentials supplement as well as its HealthPak product. The InCelligence Complex contains antioxidants such as alpha lipoic acid, resveratrol, curcumin, EGCG, olive fruit extract, rutin, quercetin, and hesperidin. The patent covers only the US formula of the InCelligence Complex.
“When we designed the InCelligence Complex, we wanted to create a formula to help the body protect itself from stress and renew youthful, normal cellular function,” says Dr. Mark Brown, USANA’s executive director of laboratory research. “I’m so proud of the work our team has done on the formulation, clinical testing, and patent submission for the InCelligence Complex. You truly don’t find this kind of dedication to the scientific method anywhere else but USANA.”*
“Our patent addresses the aging process at the subcellular level through a process called mitophagy, which may help defend against oxidative stress and subsequent damage,” says Dr. Jeremy Tian, USANA’s director of new product research. “Our formula is the first to achieve this functionality in a supplement form, and with a clear and specific molecular mechanism of action.”*
Stay Young and Healthy With the CellSentials Patented InCelligence Complex*
USANA CellSentials provide vital nutrition through essential vitamins and minerals. These are necessary for the growth, development, and long-term health of your body. However, CellSentials are more than just a multivitamin. They also contain USANA’s InCelligence Technology.*
The patented CellSentials InCelligence Technology helps activate your body’s own defense mechanisms. This helps the body protect itself from stress and renew youthful, normal cellular function. The technology uses select nutrients to support and optimize specific cellular processes. It triggers these normal processes by using your body’s cell signaling pathways—your cells’ network for sending and receiving communications.*
Using Nutrition to Signal Long-Term Health
The InCelligence Complex in Vita Antioxidant consists of a powerful blend of eight ingredients that supports a network of cell-signaling pathways. This patented combination of ingredients includes*:
- Alpha lipoic acid
- Meriva® Bioavailable Curcumin†
- Green Tea Extract
- Olivol Olive-Fruit Extract
The InCelligence Complex supports a broad range of pathways and processes for whole-body health. The two most important in the CellSentials are*:
1. The production of endogenous antioxidants—those created in cells—for powerful protection against free radicals*
Your cells are naturally equipped with powerful antioxidants. Molecules like superoxide dismutase, catalase, and glutathione are made in your cells. The nutrients in the patented InCelligence Complex help proactively support production of these natural protectors.*
It’s simple math. One dietary antioxidant molecule can eliminate one or two free-radical molecule(s). Endogenous antioxidants are typically able to neutralize 100 or more free-radical molecules during their lifespans. By encouraging the production of your natural antioxidants, the InCelligence Complex helps deliver significantly more protection. It is a powerful way to defend against an imbalance of the oxidative stress that can damage your healthy cells.*
2. The activation of mitophagy—a cellular cleanup process—to help renew efficient production of the energy that powers your cells*
Your cells produce energy (ATP—adenosine triphosphate) in the mitochondria. This cellular energy production also generates a lot of free radicals. Natural antioxidants in the cell neutralize many of the free radicals. But some mitochondria will still be damaged over time. Damaged mitochondria can work inefficiently, producing more damaging free radicals and less ATP. This makes it harder for the cell to keep up with free radical production, which leads to cellular damage.
The cell maintains efficiency through a natural response called mitophagy, which recycles the old or damaged mitochondria. So, they aren’t causing damaging reactions and the cell stays healthy. However, age or other lifestyle factors may slow this process. The InCelligence Complex helps activate mitophagy to renew efficient energy production and keep cells acting youthful.*
Nourish, Protect, and Renew Your Health With The CellSentials*
The CellSentials are your first step towards building a strong foundation for health. The broad spectrum of vitamins and minerals nourish your body. And the patented CellSentials InCelligence complex optimizes antioxidant production to protect your cells, and renew the mitochondrion in your body. This creates a comprehensive approach to support your long-term health.*
How does InCelligence Technology work ?
Instead of focusing on a single cellular process, InCelligence sends a broad range of messages to your cells. This impacts a variety of important processes, creating the most effective, holistic approach to your health.* The intricate processes and science behind USANA’s innovativeUSANA, InCelligence, science, products InCelligence complex are a game changer in the field of nutritional supplementation. In fact, the science is so groundbreaking that it can seem overwhelming if you don’t have a proper explanation. This video provides just that: a breakdown of the science of InCelligence
InCelligence and the Process of Mitophagy
The Science Behind USANA InCelligence Technology
USANA InCelligence Technology® is intelligent supplement design. It’s a nutritional technology—not a single product or a product line. InCelligence is a platform for creating products that support optimal cellular health through a natural process called cell signaling.*
This technology utilizes molecular targeting of nutrients to optimize cellular function. Key nutrients, scientifically proven to be effective cell-signaling molecules, speak your cell’s language.*
They cut through the biochemical noise—whether naturally occurring or from your lifestyle or environment—to activate your body’s abilities to support vibrant health.*
The Four Types of Nutrients and Cellular Interaction
Your diet is so much more than the calorie count. The food you eat contains a variety of nutrients. We put them in four basic categories:
- Essential Micro- and Macronutrients: Macronutrients are the big things (hence the macro)—protein, carbohydrates, and fats. Your body uses them for calories (energy), and as building material for cells. Micronutrients are found in the fruits and vegetables we eat. That’s where a lot of our vitamins and minerals come from.
- : Just the act of living, breathing, and going through your day creates damaging oxidants. That’s why you need antioxidants. Living without enough of these important nutrients can cause problems and compromise health over time. In the broadest sense, an antioxidant is any oxidant scavenger. Dietary antioxidants include vitamins and other organic compounds that neutralize oxidants at a one-for-one or one-for-two ratio. So each molecule of an antioxidant like vitamin C can take care of one or two oxidants.
- Additional Nutritional Support: These additional nutrients fall outside the category of essential vitamins and minerals. So you won’t encounter a nutritional deficiency disease without them. But they have been found to provide additional health benefits. Nutrients like lutein, zeaxanthin, and glucosamine are deposited in specific areas of the body to provide a targeted benefit—like supporting healthy vision, cognitive function, skin health, and joint health.
- USANA InCelligence Technology: We’ve known for centuries that fruits and vegetables are good for us, but scientists had to find out why. They pulled out all the big things, like vitamins, and kept digging deeper. The search led them to phytonutrients—other compounds plants make, like the ones that give them bright colors. After all, if you think about it, the best chemists in the world are plants.
In high concentrations in test tubes, the compounds were great antioxidants. But they couldn’t figure out exactly how they were still working at the lower concentrations they could achieve in the human body. Something else had to be happening.
It was cell signaling. This relatively new understanding of phytonutrients’ abilities is the basis for InCelligence technology. USANA scientists select key nutrients—like resveratrol and quercetin—that work on cell-signaling pathways to elicit health benefits inside your cells.*
Cell Signaling Basics
Your cells are intelligent. They can sense and respond to their internal and external environments through cell signaling. So at a very basic level, this process is nothing more than a cell responding to internal or external molecules.
Receptor molecules in the cells sense their internal and external environment. These interactions trigger a chain reaction (think of a line of dominoes) that can turn on genes and activate a variety of cellular responses.
There can also be signal amplification. So very small amounts of the right nutrients targeted to the right cellular landing spots can have big impacts.
Supporting Cellular Communication Pathways
Age, lifestyle, and environmental factors can make it harder for your cells to communicate effectively. InCelligence supports your cellular communication pathways, helping maintain their health and yours.
We have the ability to target specific pathways with nutrients. Supporting the free flow of cellular information allows a broad spectrum of pathways to be positively impacted. Here’s just a few examples of what supporting and turning on these cell-signaling pathways can do:
- Optimize cellular function.*
- Support a healthy immune system.*
- Support the body’s natural detoxification processes.*
- Optimize the production of powerful antioxidants made inside cells.*
- Support cellular clean-up processes.*
Cellular Strength Training for Resilience and Adaptability
Exercise strengthens your body, making it more resilient and adaptable. Your cells need the same thing. That’s why InCelligence is like strength training for your cells.
Hormesis is the scientific term you could use to describe this kind of cellular exercise. You stress cells to increase their resilience and adaptability—just like exercise stresses your body to ultimately make it stronger. The nutrients used in InCelligence complexes evolved as plants’ protection from the sun and hungry animals. So even though you’re getting a safe dose of these “cellular stressors” your cells still trigger protective responses.*
Flexing those cellular muscles helps create resilient cells that can more easily adapt to your lifestyle. Taking the proactive approach of turning on these natural processes also optimizes the natural longevity of cellular function.*
Products Made with USANA InCelligence Technology
USANA utilizes InCelligence cell-signaling technology to formulate a variety of products that provide different benefits.
USANA® CellSentials™: Contains Vita Antioxidant™ and Core Minerals™. CellSentials supplies carefully balanced levels of high-quality vitamins and antioxidants and a balanced range of highly absorbable essential minerals and trace minerals. It’s designed to provide an essential foundation of nourishment and powerful antioxidant protection. The InCelligence Complex also uses nutrients to unlock natural processes that support the health of your cells.*
HealthPak™: Convenient AM and PM packets containing Vita Antioxidant, Core Minerals, CellSentials Booster, and USANA® MagneCal D™ —a bone-health supplement that was not formulated with USANA InCelligence Technology. All the core supplements you need in one product for full support of your healthy lifestyle.*
Proglucamune™: Daily immune-support supplement with zinc and the InCelligence Beta-Glucan Complex. It supports the body’s ability to adapt and respond to the effects occasional, everyday stress or strenuous exercise can have on immune function. InCelligence Beta-Glucan Complex uses baker’s yeast and a combination of mushrooms to prime immune cells’ natural protective responses so they can effectively protect health.*
Hepasil DTX™: Comprehensive liver-support formula featuring the InCelligence Detox-Support Complex. The complex delivers a comprehensive array of phytonutrients, including green-tea extract, milk-thistle extract, broccoli concentrate, turmeric, and USANA’s unique Olivol® olive-fruit extract. This helps to activate your liver cells’ natural protective antioxidant and detoxification processes.*
Procosa®: Supports joint function and comfort. It also helps regulate normal cartilage formation that helps cushion your joints. The InCelligence Joint-Support Complex in Procosa helps trigger a process in cartilage cells that helps renew healthy joint-cell function and support healthy joint aging. The complex also influences signaling pathways that modulate your body’s natural responses to the temporary, normal inflammation resulting from exercise. This helps proactively promote a healthy immune and inflammatory response after exercise.*
CopaPrime+™: Supports peak mental performance and protects your brain health as you age with powerful nootropics: American ginseng plus the InCelligence Cognitive-Support Complex, which includes bacopa monnieri and coffee-fruit extract. CopaPrime+ works by helping your body produce an important cognitive protein needed for learning, memory, and thinking. It also helps you stay calm and focused during mentally stressful situations.*
Celavive® Skincare Products with the Cell Signaling Complex: A number of products in the Celavive skincare line reveal your natural radiance and fight the visible signs of aging with the power of the Cell Signaling Complex. These products feature InCelligence Technology by supplying targeted nutrient combinations that help revive your skin’s youthful appearance. A combination of botanicals and innovative peptides supports the natural production of compounds—collagen, hyaluronic acid, and more—that help skin look firmer and more radiant.