Answer by Dr. Ru:
- DrLact safety Score for COQ10 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of COQ10 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that COQ10 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of COQ10 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using COQ10 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by DrLact: About COQ10 usage in lactation
Coenzyme Q10 (ubiquinone) is a normal part of the diet, and is also endogenously synthesized. It is a normal component of human milk, but milk levels are slightly low in the breastmilk of mothers with preterm infants. Coenzyme Q10 has no specific lactation-related uses and no data exist on the safety and efficacy of supplementation in nursing mothers or infants. Coenzyme Q10 supplements are usually well tolerated with only infrequent, minor side effects. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information #about dietary supplements# is available elsewhere on the LactMed Web site.
what is coq10?
Coenzyme Q10 (CoQ10) is a substance that is naturally present in the human body, with the highest levels in the heart, liver, kidneys, and pancreas. It is sold in the United States as a dietary supplement. Because CoQ10 has important functions in the body and because people with some diseases have reduced levels of this substance, researchers have been interested in finding out whether CoQ10 supplements might have health benefits.
Coenzyme Q10 (CoQ10) is an antioxidant that your body produces naturally. Your cells use CoQ10 for growth and maintenance. Levels of CoQ10 in your body decrease as you age. CoQ10 levels have also been found to be lower in people with certain conditions, such as heart disease. CoQ10 is found in meat, fish and whole grains. The amount of CoQ10 found in these dietary sources, however, isn’t enough to significantly increase CoQ10 levels in your body.
As a supplement, CoQ10 supplement is available as capsules, tablets and by IV. CoQ10 might help treat certain heart conditions, as well as migraines and Parkinson’s disease.
- No serious side effects of CoQ10 have been reported. Mild side effects such as insomnia or digestive upsets may occur.
- CoQ10 may interact with the anticoagulant (blood thinner) warfarin and the diabetes drug insulin, and it may not be compatible with some types of cancer treatment.
Research on CoQ10 use for specific conditions and activities shows:
- Heart conditions. CoQ10 has been shown to improve symptoms of congestive heart failure. Although findings are mixed, CoQ10 might help reduce blood pressure. Some research also suggests that when combined with other nutrients, CoQ10 might aid recovery in people who’ve had bypass and heart valve surgeries.
- Parkinson’s disease. Early research suggests that high doses of CoQ10 might be beneficial for people in the early stages of this progressive disorder of the nervous system that affects movement.
- Statin-induced myopathy. Some research suggests that CoQ10 might help ease muscle weakness sometimes associated with taking statins.
- Migraines. Some research suggests that CoQ10 might decrease the frequency of these headaches.
- Physical performance. Because CoQ10 is involved in energy production, it’s believed that this supplement might improve your physical performance. Research in this area has produced mixed results, however.
CoQ10 supplements might be beneficial for treating conditions such as congestive heart failure and Parkinson’s disease. CoQ10 is considered safe, with few side effects. However, be sure to take this supplement under your doctor’s supervision.
Safety and side effects
CoQ10 supplements appear to be safe and to produce few side effects when taken as directed.
Mild side effects might include:
- Upper abdominal pain
- Loss of appetite
- Light sensitivity
The safety of use of CoQ10 during pregnancy and breast-feeding hasn’t been established. Don’t use CoQ10 if you’re pregnant or breast-feeding.
Possible interactions include:
- Anticoagulants. CoQ10 might make blood-thinning drugs, such as warfarin (Coumadin, Jantoven), less effective. This could increase the risk of a blood clot.
Does USANA has coenzyme Q10 ?